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« on: Apr 12th, 2018, 3:49am » |
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UNITED NATIONS Women's Paxton Lynch Jersey , April 19 (Xinhua) -- The UN Office for the Coordination of Humanitarian Affairs reported that high water levels of the Tigris left two key bridges in the Mosul area in north Iraq impassable this week, preventing displaced people from relocating to camps and emergency sites on the eastern bank, where the majority of space is available Women's Jamaal Charles Jersey , a UN spokesman told reporters here Wednesday. "Aid distributions in some camps and emergency sites were also affected, with suppliers unable to reach them," UN spokesman Stephane Dujarric said at a daily news briefing here. One of the bridges Women's Domata Peko Jersey , at Nimrud, reopened on Tuesday for civilian traffic and use by humanitarian workers, he said. However Women's Ronald Leary Jersey , a key bridge at Qayyarah is likely to take two or three more days to be repaired, the spokesman said. "It is expected that water levels will remain high for a few more days, and impact on distributions and camp construction work is likely to continue." So far Women's Menelik Watson Jersey , more than 336,000 people have been displaced from western Mosul since the start of military operations on the western neighbourhoods in late February. The cumulative number of displaced people since the beginning of the Mosul operation last fall has reached 484,000 people. The UN Population Fund's director for the Arab region Women's Shaquil Barrett Jersey , Luay Shabaneh, has just wrapped up a four-day visit to Iraq, where he met with displaced women and girls receiving services at the UN fund-supported health clinics in western and eastern Mosul. Shabaneh said he was deeply moved by the stories he heard from those uprooted by the conflict Women's Shelby Harris Jersey , the spokesman added. China reshuffles 84 corps-level military units China hopes for a united, stable and prosperous EU: Premier Li Shanghai auto show starts Three people killed in Fresno shooting spree In pics: scenery of Baiyangdian in Xiongan New Area In pics: tea garden in central China's Henan Peach blossoms on terrace fields in Guyuan, NW China's Ningxia Stewardesses for high-speed train take part in training program in Harbin WASHINGTON, Oct. 12 (Xinhua) -- Scientists said Wednesday they have used a popular gene-editing tool to successfully fix a genetic mutation that causes sickle cell anemia, taking a key step toward a cure for the blood disease. As described in the U.S. journal Science Translational Medicine, the researchers used CRISPR-Cas9 to correct the disease-causing mutation in stem cells from the blood of affected patients. Only "a proportion" of stem cells were fixed and produced healthy hemoglobin, but that is "high enough to produce a substantial benefit in sickle cell patients," they said. When implanted into mice, these corrected stem cells stuck around for at least four months, with no signs of side effects, a hint that they would also work in humans. "This is an important advance because for the first time we show a level of correction in stem cells that should be sufficient for a clinical benefit in persons with sickle cell anemia," said co-author Mark Walters, director of Benioff Oakland's Blood and Marrow Transplantation Program at the University of California (UC), San Francisco. Senior author Jacob Corn, scientific director of the Innovative Genomics Initiative at UC Berkeley, said they hope to re-infuse patients with the edited stem cells and alleviate symptoms of the disease. Corn and Walters will work together to initiate an early-phase clinical trial to test this new treatment within the next five years. "There is still a lot of work to be done before this approach might be used in the clinic, but we're hopeful that it will pave the way for new kinds of treatment for patients with sickle cell disease," Corn said. Sickle cell anemia is a blood disorder caused by a single mutation in both copies of a gene coding for beta-globin, a protein that forms part of the oxygen-carrying molecule hemoglobin. This homozygous defect causes hemoglobin molecules to stick together, deforming red blood cells into a characteristic "sickle" shape. These misshapen cells get stuck in blood vessels, causing blockages, anemia, pain, organ failure and early death. The disease is particularly prevalent in African Americans and the sub-Saharan African population, affecting hundreds of thousands of people worldwide. The researchers also noted that the approach might also able used to develop treatments for other blood diseases, severe combined immunodeficiency, chronic granulomatous disease, rare disorders like Wiskott-Aldrich syndrome and Fanconi anemia, and even HIV infection. "Sickle cell disease is just one of many blood disorders caused by a single mutation in the genome," Corn said. "It's very possible that other researchers and clinicians could use this type of gene editing to explore ways to cure a large number of diseases." HONG KONG Women's Justin Simmons Jersey , Sept. 27 (Xinhua) -- Hong Kong Exchanges and Clearing Limited (HKEX) on Wednesday announced to introduce its first ferrous metal product. It will roll out in November of this year, subject to market readiness. The iron ore futures, TSI Iron Ore Fines 62 percent Fe CFR China Futures Women's Jake Butt Jersey , will be cash-settled in U.S. dollars with both day trading and after-hours trading. It is expected to complement the HKEX's existing precious and base metals products. With the benefits of electronic trading, the planned iron ore futures will provide a transparent and efficient risk management and investment tool for physical and financial users who want to hedge their price risk or gain exposure in iron ore, said Li Gang Women's Chad Kelly Jersey , HKEX's co-head of market development. Xi says international community must cooperate on global security Int'l Conference on Intelligent Robots and Systems kicks off in Vancouver Highlights of Int'l Mongolian Dance Exhibition in Hohho.
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